With the onset of NFL betting jump-starting tomorrow with the Hall of Fame game, our staff has decided to join together for their annual gathering to project winners and losers for the upcoming season.
The following NFL odds are currently offered at BetUS Sportsbook.
2025-2026 AFC East
Buffalo Bills -325
Miami Dolphins +700
New England Patriots +550
New York Jets +1600
The preseason NFL futures for the AFC East winner suggest that the Buffalo Bills are the favorites to win the division. We agree, as there is little in-division resistance save for an improbable uprising by the Miami Dolphins.
2025-2026 AFC North
Baltimore Ravens -160
Cincinnati Bengals +250
Pittsburgh Steelers +500
Cleveland Browns +3000
The Cincinnati Bengals enter the season at full strength, but still lag behind the Baltimore Ravens in the AFC North projections. Barring an injury to Lamar Jackson, we agree that the above order will reflect the final standings.
2025-2026 AFC South
Houston Texans +105
Indianapolis Colts +350
Jacksonville Jaguars +275
Tennessee Titans +700
While the Jacksonville Jaguars have made significant improvements via the selection of wide receiver/defensive back Travis Hunter, the Houston Texans remain the class of the division and will win it for a third year in a row.
2025-2026 AFC West
Kansas City Chiefs -120
Los Angeles Chargers +300
Denver Broncos +320
Las Vegas Raiders +1400
The Chiefs aren’t getting any younger, but this is not the year that the LA Chargers surpass them. Expect KC to win the West once again.
AFC Conference Champions: The Kansas City Chiefs
The Ravens and the Bills lead the odds to win the AFC and make it to Super Bowl LX, but until either proves they can beat the Chiefs in the postseason, we’ll take a wait-and-see approach with our projections and our NFL Playoff bets.
2025-2026 NFC East
Philadelphia Eagles -145
Washington Commanders +215
Dallas Cowboys +550
New York Giants +2500
This is another set of futures where we believe the oddsmakers have correctly chosen the final standings. If these odds prove accurate, this could be the end of the Dak Prescott era in Dallas.
2025-2026 NFC North
Detroit Lions +145
Green Bay Packers +250
Minnesota Vikings +325
Chicago Bears +475
This is arguably the toughest division in pro football. The Lions are selected as the odds-on favorite to win the NFC North, but the Packers are not far behind in the odds. The Vikings and Bears also feature young rosters that are loaded with talent and should challenge for a wild-card spot this year.
2025-2026 NFC South
Tampa Bay Buccaneers -110
Atlanta Falcons +225
Carolina Panthers +400
New Orleans Saints +1400
The Buccaneers lead the NFC South futures and should have just enough firepower to stave off the developing Falcons. The Panthers and Saints are light-years away from legitimacy.
2025-2026 NFC West
San Francisco 49ers +160
Los Angeles Rams +170
Seattle Seahawks +500
Arizona Cardinals +450
While the Rams and 49ers are neck-and-neck in the odds to win the NFC West, San Francisco has the easiest strength of schedule for 2025-26. The lack of quality opponents should assist the 49ers in acquiring a top playoff seed in the NFC.
NFC Conference Champions: The San Francisco 49ers
The Eagles are hundreds of points ahead of the second-place contender in the latest NFC futures, but we’re projecting a return to form for the 49ers as they make their final run at a championship with this core lineup.
Super Bowl LX Champions: The San Francisco 49ers
While QB Brock Purdy is very young, there is still a massive sense of urgency to win a title immediately in Northern California. We believe this is the year they put it all together and get revenge against the Chiefs, who they lost to in Super Bowls LIV and LVIII.
Super Bowl betting sites are featuring the 49ers at +2000 to go all the way this year.
Entertainment
Big Brother Betting Preview For Season 27
