The first round of the 2025 MLS Cup Playoffs are now underway, with this year’s bracket reflecting a level of parity rarely seen in league history. The Philadelphia Union, who clinched the Supporters’ Shield with 66 points, lead a postseason field where only 13 points separated first from fourteenth in the regular season. This is a gap that has not been this narrow in nearly a decade.
Both the wild-card and early knockout rounds have already produced upsets, underscoring the unpredictability of the new playoff format, which features a best-of-three first round followed by single-elimination matches.
With perennial favorites and new contenders vying for the championship, analysts note that the absence of a dominant team sets the stage for one of the most competitive and open playoff campaigns in recent memory.
2025 Audi MLS Playoff Schedule
- Round One Best-of-3 Series: Through November 9th
- Conference Semifinals: November 22nd and 23rd
- Conference Finals: November 29th and 30th
- MLS Cup – December 6th
Online MLS betting sites have game lines and futures available for action right now. The current Major League Soccer futures suggest that the most likely winners are Inter Miami, the Philadelhia Union, and Vancouver Whitecaps, none of whom have won the MLS Cup before.
MLS Futures
- Inter Miami +350
- Philadelphia Union +450
- Vancouver Whitecaps +500
- San Diego FC +700
- Los Angeles FC +800
- FC Cincinnati +1000
- Seattle Sounders +1600
- Columbus Crew +2000
- New York City FC +2200
- Minnesota United +2500
- Charlotte FC +2500
- Nashville SC +5000
- Chicago Fire +5000
- Austin FC +5000
- Portland Timbers +5000
- FC Dallas +8000
Inter Miami
Inter Miami stands out as the strongest contender for the 2025 MLS Cup, boasting unrivaled individual talent led by Lionel Messi, who just claimed the Golden Boot with a late-season scoring surge.
The team’s depth, experience, and ability to perform under pressure are complemented by a leadership core determined to secure a first-ever league title before marquee players retire.
Philadelphia Union
The Philadelphia Union is primed to capture its first MLS Cup thanks to a league-best defensive record and home-field advantage throughout the playoffs. Led by finalists for Defender of the Year Jakob Glesnes and Kai Wagner, the Union conceded the fewest goals with disciplined, organized play.
With depth in both midfield and attack, plus a coaching staff known for tactical adaptability, Philadelphia’s collective strength and experience could allow them to break through for the elusive title this year.
Vancouver Whitecaps
Soccer sportsbooks are offering 5-to-1 payouts on wagers placed on Vancouver to win it all. Star signings like Thomas Müller have elevated their offensive attack, while a deep roster led by coach Jesper Sørensen thrives on relentless possession and team unity.
Their ability to dominate matches and create chances, as shown in their playoff-opening rout, and the passionate support at BC Place give Vancouver a true edge as contenders for the league’s top prize.
MLS Playoff Odds Provided By Bovada Sportsbook (review) | MLS Soccer Official Website
