The first round of the 2025 US Open began yesterday in New York City, marking the 145th edition of the tournament and the season’s final Grand Slam held on the iconic hard courts of the USTA Billie Jean King National Tennis Center.
Tennis superstars and rising talents will compete for a record $5 million singles champion prize, with the women’s final happening on September 6, and the men’s on September 7th.
This year’s field includes defending champions and legendary veterans among those chasing glory. Odds for betting on the US Open are now available, with lines for individual matches, futures for winners, and tennis props for numerous other tournament-related outcomes.
US Open – Men
The men’s singles bracket at the 2025 US Open is stacked with top talent, led by defending champion and No. 1 seed Jannik Sinner and No. 2 seed Carlos Alcaraz, who have dominated recent Grand Slam finals.
Fans expect a showdown between these young rivals in the later rounds. Former champion Novak Djokovic is still a legitimate contender, and Taylor Fritz, who reached last year’s final, is also a popular betting favorite.
Men’s Odds To Win The 2025 US Open
Jannik Sinner EVEN
Carlos Alcaraz +150
Novak Djokovic +1200
Alexander Zverev +1800
Jack Draper +1800
Ben Shelton +2000
Taylor Fritz +2500
Daniil Medvedev +5000*
Holger Rune +6600
Alex De Minaur +6600
Jakub Mensik +8000
The first round has already proved chaotic, as Daniil Medvedev’s match against Benjamin Bonzi was interrupted when a photographer prematurely stepped onto the court during match point.
The umpire allowed Bonzi a redo of his first serve, prompting Medvedev to angrily confront the official and rile the crowd. The match was delayed by more than six minutes as Medvedev’s supporters loudly protested.
Although Medvedev fought back to extend the match, Bonzi ultimately won in five sets. The photographer was removed by security and had credentials revoked for the rest of the tournament. Medvedev later showed frustration by smashing his racket post-match.
Men’s Former US Open Winners Competing
- Jannik Sinner (defending champion; winner in 2024)
- Novak Djokovic (three-time champion: 2011, 2015, 2018)
- Carlos Alcaraz (winner in 2022)
- Daniil Medvedev (winner in 2021)*
*Already eliminated in 2025
Our Prediction: Carlos Alcaraz
Sleeper: Taylor Fritz
US Open – Women
The women’s singles bracket at the 2025 US Open features a star-studded lineup that includes defending champions and returning legends. With 128 players in the field and fierce first-round matchups, contenders like Madison Keys, Jasmine Paolini, and rising talents Mirra Andreeva and Emma Navarro aim to disrupt the favorites.
Two-time winner Venus Williams also returns as a wild card, allowing younger fans to get a glimpse of an all-time great in action.
Women’s Odds To Win The 2025 US Open
Iga Swiatek +225
Aryna Sabalenka +300
Coco Gauff +700
Mirra Andreeva +1100
Elena Rybakina +1100
Naomi Osaka +1600
Madison Keys +2000
Emma Raducanu +2000
Victoria Mboko +2000
Amanda Anisimova +2200
Jessica Pegula +2500
Jasmine Paolini +5000
Elina Svitolina +5000
Online tennis sportsbooks have placed Swiatek and Sabalenka closely together at the top of the field, with Gauff listed third at +700.
Women’s Former US Open Winners Competing
- Aryna Sabalenka (defending champion; winner in 2024)
- Iga Swiatek (winner in 2022)
- Coco Gauff (winner in 2023)
- Emma Raducanu (winner in 2021)
- Venus Williams (winner in 2000, 2001)
Our Prediction: Coco Gauff
Sleeper: Jasmine Paolini
Sources: 2024 US Open Odds Provided By BetUS Sportsbook | Yahoo! Sports
