The 2025 college football season kicks off this Saturday with five matchups. Officially referred to as Week 0, these five games feature betting lines at the top online college football sportsbooks that are taking action now.
The following preview for college football betting breaks down the odds, highlights key matchups, and offers expert predictions for this exciting start to the new season.
Iowa State (#21) vs. Kansas State (#20)
- Point Spread: Cyclones +3.0 (-105), Wildcats -3.0 (-115)
- Moneline: Cyclones +135, Wildcats -160
- Over: 49.5 (-115)
- Under: 49.5 (-105)
- ESPN – 12:00 PM
The first game of the NCAAF season will be a Big 12 matchup that takes place at Aviva Stadium in Dublin, Ireland. Kansas State is favored by a field goal, which would avenge their 29-21 loss on the road in 2024.
We’re calling for the upset here and project a narrow Cyclones win on Saturday.
UNLV @ Idaho State
- Point Spread: Rebels -25.5 (-110), Bengals +25.5 (-110)
- Moneline: Rebels [offline], Bengals [offline]
- Over: 63.5 (-110)
- Under: 63.5 (-110)
- 4:00 PM
UNLV vs. Idaho State betting lines are hard to find, but the above odds are posted at MyBookie. The reason lines are off the boards is due to the lopsided nature of the point spread that favors the Rebels by 25.5 points. This game shouldn’t be much of a contest, with UNLV wrapping it up by halftime.
From a betting perspective, we’re laying off of this game because of the potential for the Rebels to lay an egg offensively.
Fresno State @ Kansas
- Point Spread: Bulldogs +13.0 (-115), Jayhawks -13.0 (-105)
- Moneline: Bulldogs +370, Jayhawks -510
- Over: 50.5 (-110)
- Under: 50.5 (-110)
- FOX – 6:30 PM
Fresno State is nearly a two-touchdown underdog on the road to the Kansas Jayhawks of the Big 12. We like FSU to turn in a solid performance this Saturday and cover the 13 points, losing by 10 or less.
Sam Houston State @ Western Kentucky
- Point Spread: Bearkats +10.0 (-115), Hilltoppers -10.0 (-105)
- Moneline: Bearkats +295, Hilltoppers -390
- Over: 61.0 (-105)
- Under: 61.0 (-115)
- CBSSN – 7:00 PM
The WKU Hilltoppers are favored by 10 points at home in Bowling Green, KY, to start the season out against the Sam Houston State Bearkats. We believe that WKU will jump out in front early and remain ahead of the Bearkats by at least ten points for the remainder of the contest.
Stanford @ Hawaii
- Point Spread: Cardinal +2.5 (-110), Rainbow Warriors -2.5 (-110)
- Moneline: Cardinal +110, Rainbow Warriors -130
- Over: 52.5 (-115)
- Under: 52.5 (-105)
- CBS – 7:30 PM
The Stanford Cardinal of the ACC are 2.5-point underdogs on the road in Hawaii when they close out Week 0’s action against the Rainbow Warriors. We like Stanford to cover the spread and win this game on the road to get out to a 1-0 start to the season.
Sources: Bovada Sportsbook | MyBookie Sportsbook | ESPN
